News & insights

News & insights

Updates on our capabilities, case studies from our programmes, and perspectives on enabling formulation and bioavailability enhancement.

  • Auralis Bio expands spray-drying capacity for clinical-scale amorphous dispersions

    Auralis Bio has commissioned additional spray-drying and downstream processing capability, shortening the path from feasibility screen to first GMP clinical supply for solubility-limited candidates and adding redundancy for partner programmes.

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  • Case study: a 9-fold increase in oral exposure for a first-pass-limited candidate

    For a lipophilic compound with low and variable oral exposure, a self-emulsifying (SEDDS) delivery system raised relative bioavailability roughly nine-fold in preclinical models and cut variability, enabling the partner to commit the molecule to IND-enabling studies.

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  • Auralis Bio joins consortium advancing predictive biopharmaceutics

    Auralis Bio has joined a pre-competitive consortium applying PBPK modelling and biorelevant dissolution to link in vitro formulation performance to in vivo exposure earlier, reducing the number of animal studies needed to select an enabling formulation.

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